To cultivate pharmacy service-oriented professionals who possess both medical and pharmaceutical expertise, optimizing the construction of core courses in clinical pharmacy and enhancing students’ practical abilities are of utmost importance. Taking the diagnostics on-line and off-line blended first-class course at Shenyang Pharmaceutical University as an example, we have utilized high-quality online resources that complement offline teaching and conducted multiple cycles of teaching practice to improve the content design, the process of organization and implementation, the reform of teaching methods and assessment methods as well as the evaluation of teaching effect. Finally, we constructed core courses suitable for the educational goal of clinical pharmacy specialty. The new teaching mode enhances students' practical ability, improves their learning experience, and achieves good teaching effect. In the meanwhile, it provides a reference for the construction of core undergraduate courses in clinical pharmacy in China.

diagnostics, first-class undergraduate course, on-line and off-line blended teaching, undergraduate teaching reform, clinical pharmacy